CLINICAL EVIDENCE

Clinical Trials, Papers and Studies Involving the Effectiveness of Silicone Gel in Managing Scars

  1. Mustoe, T. (2007). “Evolution of Silicone Therapy and Mechanism of Action in Scar Management”. Aesthetic Plastic Surgery, 2008, 32:82-92
  2. Atiyeh, B. (2007). “Nonsurgical Management of Hypertrophic Scars: Evidence-Based Therapies, Standard Practices, and Emerging Methods. Aesthetic Plastic Surgery, 2007, 31:468-492
  3. Mustoe, T., Cooter, R., Gold, M., Hobbs, F., Ramelet, A., Shakespeare, P., Stella, M., Teot, L., Wood, F., Ziegler, U. for the International Advisory Panel on Scar Management. (2002). “International Clinical Recommendations on Scar Management”. Plastic and Reconstructive Surgery, August 2002, 110(2): 560-571
  4. Borgognoni, L.( 2002). “Biological Effects of Silicone Gel Sheeting”. Wound Repair and Regeneration, March-April, 2002, 10(2): 118-121
  5. Gold, M., Foster, T., Adair, M., Burlinson, K., Lewis, T., (2001). “Prevention of Hypertrophic Scars and Keloids by the Prophylactic Use of Topical Silicone Gel Sheets Following a Surgical Procedure in an Office Setting”. Dermatologic Surgery, 27:641-644
  6. Chernoff, W., Cramer, H., Su-Huang, S.( 2007). “The Efficacy of Topical Silicone Gel Elastomers in the treatment of Hypotrophic Scars, Keloid Scars and Postlaser Exfoliation Erythema”. Aesthetic Plastic Surgery, 2007, 31(3):495-500
  7. Li-Tsang, C., Lau, J., Chan, Y., Ho, M.( 2006). “A Prospective Randomized Clinical Trial to Investigate the Effect of Silicone Gel Sheeting on Posttraumatic Hypertrophic Scarring among the Chinese Population”. Burns, 32:678-683
  8. Majan, J.( 2006). “Evaluation of a self-adherent soft silicone dressing for the treatment of hypertrophic postoperative scars”. Journal of Wound Care, 15:193-196
  9. Chan, K., Lau, C., Adeeb, S., Somasundaram, S., Nasir-Zahari, M. (2005). “A Randomized, Placebo-controlled, Double-blind, Prospective Clinical Trial of Silicone Gel in Prevention of Hypertrophic Scar Development in Median Sternotomy Wound”. Plastic Reconstructive Surgery, 116:1013-1020
  10. de Oliveira, G., Nunes, T., Magna, L., Cintra, M., Kitten, G., Zarpellon, S., Raposo Do Amaral, C. (2001). “Silicone Versus Nonsilicone Gel Dressings: A Controlled Trial”. Dermatologic Surgery, 27:721-726
  11. Borgognoni, L., Martini, L., Chiarugi, C., Gelli, R., Reali, U. (2000). “Hypertrophic Scars and Keloids: Immunophenotypic Features and Silicone Sheets to Prevent Recurrences”. Annals of Burns and Fire Disasters, 8:164-169
  12. Cruz-Jorchin, N. (1996). “Effectiveness of Silicone Sheets in the Prevention of Hypertrophic Breast Scars”. Annals of Plastic Surgery, 37:345-348
  13. Sproat, J., Dalcin, A., Weitauer, N., Roberts, R. (1992). “Hypertrophic Sternal Scars: Silicone Gel Sheets Versus Kenalog Injection Treatment”. Plastic Reconstructive Surgery, 90:988-992
  14. Ahn, S., Monafo, W., Mustoe, T. (1991). “Topical Silicone Gel for the Prevention and Treatment of Hypertrophic Scars. Archives of Surgery, 126:499-504
  15. Ahn, S., Monafo, W., Mustoe, T. (1989). “Topical Silicone Gel: A New Treatment for Hypertrophic Scars. Surgery 106:787-787
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